1. Scope
1.1 This test method describes the determination of lipid components in liposomal formulations,
which includes sample solubilization in methanol followed by separation of the analytes
using ultra-high-performance liquid chromatography (UHPLC) and detection with tandem
mass-spectrometry (MS/MS). This test method adheres to multiple reaction monitoring
(MRM) mass spectrometry on a triple quadrupole mass spectrometer (TQMS).