Radiological protection. Minimum criteria for electron paramagnetic resonance (EPR) spectroscopy for retrospective dosimetry of ionizing radiation - General principles

Radiological protection. Minimum criteria for electron paramagnetic resonance (EPR) spectroscopy for retrospective dosimetry of ionizing radiation - General principles

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What is ISO 13304-1 about?  

ISO 13304 discusses radiological protection. ISO 13304-1 is the first part of the ISO 13304 multi-series and discusses minimum criteria for electron paramagnetic resonance spectroscopy. ISO 13304-1 provides minimum acceptable criteria required to establish a procedure for retrospective dosimetry by electron paramagnetic resonance spectroscopy and to report the results.  

The second purpose is to facilitate the comparison of measurements related to absorbed dose estimation obtained in different laboratories. ISO 13304-1 covers the determination of absorbed dose in the measured material. It does not cover the calculation of dose to organs or to the body. It covers measurements in both biological and inanimate samples, and specifically 

  • Based on inanimate environmental materials like glass, plastics, clothing fabrics, saccharides, etc., usually made at X-band microwave frequencies (8 GHz to 12 GHz) 
  • In vitro tooth enamel using concentrated enamel in a sample tube, usually employing X-band frequency, but higher frequencies are also being considered 
  • In vivo tooth dosimetry, currently using L-band (1 GHz to 2 GHz), but higher frequencies are also being considered 
  • In vitro nail dosimetry using nail clippings measured principally at X-band, but higher frequencies are also being considered 
  • In vivo nail dosimetry with the measurements made at X-band on the intact finger or toe 
  • In vitro measurements of bone, usually employing X-band frequency, but higher frequencies are also being considered 

Note: The dose referred to in ISO 13304-1 is the absorbed dose of ionizing radiation in the measured materials. 

Who is ISO 13304-1 for? 

ISO 13304-1 on radiological protection (electron paramagnetic resonance) is useful for: 

  • Nuclear plants 
  • Health and Safety bodies 
  • Doctors  

Why should you use ISO 13304-1 

Electron paramagnetic resonance (EPR) has become an important approach for retrospective dosimetry in any situation where dosimetric information is potentially incomplete or unknown for an individual. It is now applied widely for retrospective evaluation of doses that were delivered at considerable times in the past and has received attention for use for triage after an incident in which large numbers of people have potentially been exposed to clinically significant levels of radiation.  

ISO 13304-1 is aimed to make this technique more widely available, more easily applicable, and useful for dosimetry. Specifically, ISO 13304-1 proposes a methodological frame and recommendations to set up, validate, and apply protocols from sample collection to dose reporting. The application of ISO 13304-1 to ex vivo human tooth enamel dosimetry.