Leather. Chemical determination of the preservative (TCMTB, PCMC, OPP, OIT) content in leather by liquid chromatography - Acetonitrile extraction method

Leather. Chemical determination of the preservative (TCMTB, PCMC, OPP, OIT) content in leather by liquid chromatography - Acetonitrile extraction method

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What is ISO 13365-1 about? 

ISO 13365-1 is the first part of the multi-series ISO 13365. ISO 13365-1 specifies a test method by acetonitrile solvent extraction for the determinate one of the total contents (solvent extractible) of the following preservative agents in leather by liquid chromatography: 

  • 2-(thiocyanomethylthio)-benzothiazole (TCMTB) 
  • 4-chloro-3-methyl phenol (PCMC) 
  • 2-phenyl phenol (OPP) 
  • 2-octylisothiazol-3(2H)-one (OIT) 

ISO 13365-1 can also be used to determine breakdown products of these preservative agents, which protect the leather from microbiological attacks. 

Who is ISO 13365-1 for? 

ISO 13365-1 on the chemical determination of the preservative in leather is useful for: 

  • Leather manufacturing industries  
  • Leather testers 
  • Chemical laboratories  

Why should you use ISO 13365‑1?  

Liquid chromatography (LC) is an analytical chromatographic technique that is useful for separating ions or molecules that are dissolved in a  solvent. 

ISO 13365-1 states some specific chemicals to determine the preservatives which are as follows: 

  • 2-(thiocyanomethylthio)-benzothiazole (TCMTB): to control the growth of fungi and sulphate reducing bacteria  
  • 4-chloro-3-methyl phenol (PCMC): for maintaining low toxicity and quality performance of the product 
  • 2-phenylphenol (OPP): for the safety and protection purpose of the end-users 
  • 2-octylisothiazol-3(2H)-one (OIT): it is low toxicity, easy to operate, for protection purpose 

ISO 13365-1 is beneficial for making good quality leather. 

What is changed since the last update? 

BS EN ISO 13365-1:2020 supersedes ISO 13365:2011. BS EN ISO 13365-1:2020includes some technical changes with respect to ISO 13365:2011. These include: 

  • The title has been changed to indicate the method of extraction 
  • The use of HPLC with mass spectrometric (MS) detection has been included 
  • Reagents have been technically modified. 
  • The chromatographic conditions (previously in 6.3) are now included in a new annex also include additional conditions for use with MS detection.